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Immunohistochemical expression of SP-NK-1R-EGFR pathway and VDR in colonic inflammation and neoplasia.

Authors
  • Isidro, Raymond A1
  • Cruz, Myrella L1
  • Isidro, Angel A1
  • Baez, Axel1
  • Arroyo, Axel1
  • González-Marqués, William A1
  • González-Keelan, Carmen1
  • Torres, Esther A1
  • Appleyard, Caroline B1
  • 1 Raymond A Isidro, Myrella L Cruz, Angel A Isidro, Caroline B Appleyard, Department of Physiology and Pharmacology, Ponce School of Medicine and Health Sciences, Ponce, PR 00732, United States.
Type
Published Article
Journal
World journal of gastroenterology
Publication Date
Feb 14, 2015
Volume
21
Issue
6
Pages
1749–1758
Identifiers
DOI: 10.3748/wjg.v21.i6.1749
PMID: 25684939
Source
Medline
Keywords
License
Unknown

Abstract

Immunohistochemical NK-1R and pEGFR positivity with VDR negativity can be used to identify areas of sporadic colorectal neoplasia. VDR immunoreactivity can distinguish CAC from sporadic cancer.

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