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Immunoexpression of interleukin 17 in apical periodontitis lesions.

Authors
  • Ajuz, Natasha C1
  • Antunes, Henrique2
  • Mendonça, Thais A3
  • Pires, Fábio R1
  • Siqueira, José F Jr1
  • Armada, Luciana4
  • 1 Department of Endodontics and Immunohistochemistry Laboratory, Faculty of Dentistry, Estácio de Sá University, Rio de Janeiro, RJ, Brazil. , (Brazil)
  • 2 Department of Endodontics and Immunohistochemistry Laboratory, Faculty of Dentistry, Estácio de Sá University, Rio de Janeiro, RJ, Brazil; Department of Endodontics, Faculty of Dentistry, Grande Rio University, Duque de, Caxias, RJ, Brazil. , (Brazil)
  • 3 Department of Endodontics, Faculty of Dentistry, Grande Rio University, Duque de, Caxias, RJ, Brazil. , (Brazil)
  • 4 Department of Endodontics and Immunohistochemistry Laboratory, Faculty of Dentistry, Estácio de Sá University, Rio de Janeiro, RJ, Brazil. Electronic address: [email protected] , (Brazil)
Type
Published Article
Journal
Journal of endodontics
Publication Date
Sep 01, 2014
Volume
40
Issue
9
Pages
1400–1403
Identifiers
DOI: 10.1016/j.joen.2014.03.024
PMID: 25043329
Source
Medline
Keywords
License
Unknown

Abstract

The present study reinforces the notion that IL-17 may take part in the pathogenesis of apical periodontitis lesions. A role in the exacerbation of chronic inflammation and cyst formation is suspected. Further studies are required to shed light on the specific functions of IL-17 in periradicular inflammatory processes.

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