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[Immunoblastic lymphadenitis: pathohistologic picture and differential diagnosis from malignant lymphoma].

Authors
  • Pavlovskaia, A I
  • Probatova, N A
Type
Published Article
Journal
Arkhiv patologii
Publication Date
Jan 01, 1995
Volume
57
Issue
5
Pages
21–25
Identifiers
PMID: 8579489
Source
Medline
License
Unknown

Abstract

Immunoblastic lymphadenitis is a T-cell immune hyper-response to antigenic stimulation. Patho-histologically, polymorphic hyperplasia of the lymph node pulp with a widening of the paracortical zone and the disturbance of the node structure is found. The cells of the paracortical proliferate are represented by small lymphocytes, stimulated lymphoid cells of varying size with numerous immunoblasts, plasma cells at various stages of maturation including lymphoplasmocytoid ones. When the structure of the lymph node is disturbed immunohistochemical examination is necessary to reject malignant lymphoma.

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