Immunobiologic effects of cytokine gene transfer of the B16-BL6 melanoma.
Department of Otolaryngology, Division of Hematology and Oncology, University of Michigan, Ann Arbor, USA.
- Published Article
Archives of otolaryngology--head & neck surgery
- Publication Date
Dec 01, 1993
We observed diverse immunobiologic effects associated with cytokine gene transfer into the B16-BL6 melanoma. Interleukin 4 transfection of tumor resulted in decreased in vivo tumorigenicity that may be related to a host immune response. Further studies to evaluate the host T-cell response to these gene-modified tumors are being investigated.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/17431982