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Immuno-chemotherapy reduces recurrence of malignant pleural mesothelioma: an experimental setting.

Authors
  • Ampollini, Luca
  • Soltermann, Alex
  • Felley-Bosco, Emanuela
  • Lardinois, Didier
  • Arni, Stephan
  • Speck, Roberto F
  • Weder, Walter
  • Opitz, Isabelle
Type
Published Article
Journal
European Journal of Cardio-Thoracic Surgery
Publisher
Oxford University Press
Publication Date
Mar 01, 2009
Volume
35
Issue
3
Pages
457–462
Identifiers
DOI: 10.1016/j.ejcts.2008.11.030
PMID: 19162494
Source
Medline
License
Unknown

Abstract

Adjuvant treatment with chemotherapy or immuno-chemotherapy leads to significant reduction of mesothelioma recurrence after surgery in this rat MPM model. Immuno-chemotherapy resulted in an increased recruitment of inflammatory cells to the site of tumourigenesis and elicited higher level of tumour growth inhibiting cytokines.

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