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Immunization with HBsAg-Fc fusion protein induces a predominant production of Th1 cytokines and reduces HBsAg level in transgenic mice.

Authors
Type
Published Article
Journal
Chinese medical journal
Publication Date
Volume
125
Issue
18
Pages
3266–3272
Identifiers
PMID: 22964321
Source
Medline

Abstract

HBsAg-Fc is effective in eliciting both the humoral and cellular immune responses against HBsAg in HBsAg transgenic mice, which makes it a potential immunogen for the immunotherapy of chronic hepatitis B.

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