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Immunization against a rat colon carcinoma by sodium butyrate-treated cells but not by interleukin 2-secreting cells.

Authors
  • Patry, Y
  • Douillard, J Y
  • Meflah, K
  • Le Pendu, J
Type
Published Article
Journal
Gastroenterology
Publisher
Elsevier
Publication Date
Nov 01, 1995
Volume
109
Issue
5
Pages
1555–1565
Identifiers
PMID: 7557139
Source
Medline
License
Unknown

Abstract

Interleukin 2-secreting cells efficiently vaccinated animals when injected while replicating but not after irradiation. Conversely, sodium butyrate pretreatment provided a simple and efficient vaccination scheme that generated a long-term immune memory and allowed the use of irradiated cells.

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