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Immune and inflammatory pathways in NASH.

Authors
  • Ganz, Michal
  • Szabo, Gyongyi
Type
Published Article
Journal
Hepatology international
Publication Date
Dec 01, 2013
Volume
7 Suppl 2
Pages
771–781
Identifiers
DOI: 10.1007/s12072-013-9468-6
PMID: 24587847
Source
Medline
Keywords
License
Unknown

Abstract

Immune and inflammatory pathways have a central role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Both the innate and adaptive immune systems contribute to the development of NAFLD. Pathogen-associated molecular patterns and danger-associated molecular patterns are known to activate a variety of pattern-recognition receptors that result in inflammation. The key features of the immune system and inflammatory pathways in the development of NAFLD are discussed in this review.

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