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Immobilized Whole-Cell Transaminase Biocatalysts for Continuous-Flow Kinetic Resolution of Amines

Authors
  • molnár, zsófia
  • farkas, emese
  • lakó, ágnes
  • erdélyi, balázs
  • kroutil, wolfgang
  • vértessy, beáta g.
  • paizs, csaba
  • poppe, lászló
Publication Date
May 10, 2019
Source
MDPI
Keywords
Language
English
License
Green
External links

Abstract

d. The batch and continuous-flow mode kinetic resolutions with transaminase biocatalyst of opposite stereopreference provided access to both enantiomers of the corresponding amines. By using the most suitable immobilized transaminase biocatalysts, this study describes the first transaminase-based approach for the production of both pure enantiomers of 1-(3,4-dimethoxyphenyl)ethan-1-amine 1d.

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