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[IgG4 levels in polyvalent immunoglobulins and immunoglobulins prepared by precipitation with caprylic acid].

Authors
Type
Published Article
Journal
Revue française de transfusion et immuno-hématologie
Publication Date
Volume
29
Issue
5
Pages
347–353
Identifiers
PMID: 3576044
Source
Medline
License
Unknown

Abstract

Levels of IgG4 in immunoglobulin preparations obtained either by conventional ethanol fractionation or by ethanol and caprylic acid fractionation (Allergam) were measured by an enzyme-immunoassay (competitive Elisa). In 9 ethanol preparations, the mean percentage of IgG4 was 2.1% +/- 0.5. In 10 preparations of Allergam, the mean percentage of IgG4 was 4.6% +/- 1. The concentration of IgG4 in Allergam preparations is about twice the concentration found in conventional ethanol preparations.

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