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IgG and IgM antibodies immunoreacting with a 2,3-diacyl trehalose-2'-sulphate in sera from leprosy patients.

Authors
  • Cruaud, P
  • Potar, M C
  • David, H L
  • Papa, F
  • Torgal-Garcia, J
  • Maroja, F
  • Orsi-Souza, A T
Type
Published Article
Journal
Zentralblatt für Bakteriologie : international journal of medical microbiology
Publication Date
Jun 01, 1990
Volume
273
Issue
2
Pages
209–215
Identifiers
PMID: 2119181
Source
Medline
License
Unknown

Abstract

The distribution of IgG and IgM antibodies immunoreacting with the sulpholipid I (SLI) and sulpholipid IV (SLIV) of Mycobacterium tuberculosis was examined in sera from leprosy patients. It was found that the immunological reactions correlated with the clinical spectrum of leprosy; and in multibacillary patients, antibody titres declined in response to successful treatment. The serological patterns were similar to the PGL I patterns, however, the IgG responses towards the sulpholipids were predominant over the IgM responses in the case of the sulpholipid antigens.

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