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IgA1-containing immune complexes in IgA nephropathy differentially affect proliferation of mesangial cells.

Authors
  • Novak, Jan
  • Tomana, Milan
  • Matousovic, Karel
  • Brown, Rhubell
  • Hall, Stacy
  • Novak, Lea
  • Julian, Bruce A
  • Wyatt, Robert J
  • Mestecky, Jiri
Type
Published Article
Journal
Kidney international
Publication Date
Feb 01, 2005
Volume
67
Issue
2
Pages
504–513
Identifiers
PMID: 15673298
Source
Medline
License
Unknown

Abstract

Overall, these findings suggest that CIC containing aberrantly glycosylated IgA1 affect proliferation of MC in vitro and, thus, likely play a role in the pathogenesis of IgAN.

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