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Ifosfamide/etoposide combination in the treatment of recurrent malignant solid tumors of childhood. A Pediatric Oncology Group Phase II study.

Authors
  • Kung, F H
  • Pratt, C B
  • Vega, R A
  • Jaffe, N
  • Strother, D
  • Schwenn, M
  • Nitschke, R
  • Homans, A C
  • Holbrook, C T
  • Golembe, B
Type
Published Article
Journal
Cancer
Publication Date
Mar 01, 1993
Volume
71
Issue
5
Pages
1898–1903
Identifiers
PMID: 8448755
Source
Medline
License
Unknown

Abstract

Ifosfamide/VP-16 is an active combination in children with recurrent malignant solid tumors. Although it was myelosuppressive, the incidence of infection was quite low (3.6%). Mesna was very effective in preventing the development of hematuria.

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