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[Idiopathic interstitial pneumonia associated with a high level of CA19-9 in serum and with CA19-9 in lung tissue].

Authors
  • Sugiyama, M
  • Ito, K
  • Iyonaga, K
  • Yamaguchi, T
  • Doi, T
  • Saita, N
  • Yamasaki, H
  • Kohrogi, H
  • Suga, M
  • Ando, M
Type
Published Article
Journal
Nihon Kyōbu Shikkan Gakkai zasshi
Publication Date
May 01, 1997
Volume
35
Issue
5
Pages
561–565
Identifiers
PMID: 9234636
Source
Medline
License
Unknown

Abstract

A 65-year-old man was admitted to our hospital because of mild dyspnea. A chest roentgenogram showed diffuse reticulonodular shadows in both lung fields. The concentration of CA19-9 in serum was high. Pancreatic cancer and other diseases were considered as causes, but no definitive diagnosis could be made. An open-lung biopsy was done, and examination of a specimen resulted in the diagnosis of idiopathic interstitial pneumonia (chronic type). Immunohistochemical staining with anti-CA19-9 antibody was positive. The lumens of microscopic honeycomb structures and fibrotic areas were covered with flattened and cuboidal metaplastic epithelial cells, which stained positively for anti-CA19-9 antibody.

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