Identify potential drugs for cardiovascular diseases caused by stress-induced genes in vascular smooth muscle cells.

Authors

• Victor Kok
• Huang, Chien-Hung¹
• Ciou, Jin-Shuei²
• Chen, Shun-Tsung²
• Kok, Victor C³
• Chung, Yi²
• Tsai, Jeffrey J P²
• Kurubanjerdjit, Nilubon⁴
• Huang, Chi-Ying F⁵
• Ng, Ka-Lok⁶

• ¹ Department of Computer Science and Information Engineering, National Formosa University , Yun-Lin , Taiwan.
• ² Department of Bioinformatics and Medical Engineering, Asia University , Taichung , Taiwan.
• ³ Department of Bioinformatics and Medical Engineering, Asia University, Taichung, Taiwan; Division of Medical Oncology, Kuang Tien General Hospital Cancer Center, Taichung, Taiwan.
• ⁴ School of Information Technology, Mae Fah Luang University , Chiang Rai , Thailand.
• ⁵ Institute of Biopharmaceutical Sciences, National Yang-Ming University , Taipei , Taiwan.
• ⁶ Department of Bioinformatics and Medical Engineering, Asia University, Taichung, Taiwan; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan.

Type

Published Article

Journal

PeerJ

Publication Date

Jan 01, 2016

Volume

4

Identifiers

PMID: 27703845

Source

Medline

Keywords

• Cardiovascular Disease
• Vascular Smooth Muscle Cell
• Mechanical Stress
• Drug Repositioning
• Gaussian Graphical Model
• Gene Set Enrichment Analysis
• Time-Course Microarray
• Topological Parameters

License

Unknown