Identification of transport abnormalities in duodenal mucosa and duodenal enterocytes from patients with cystic fibrosis.
- Authors
- Type
- Published Article
- Journal
- Gastroenterology
- Publisher
- Elsevier
- Publication Date
- Jun 01, 2000
- Volume
- 118
- Issue
- 6
- Pages
- 1051–1060
- Identifiers
- PMID: 10833480
- Source
- Medline
- License
- Unknown
Abstract
These findings implicate CFTR in NL duodenal alkaline transport and its absence in CF. Although duodenal bicarbonate secretion is impaired in CF tissues, alternate pathway(s) likely exist that can be activated by carbachol and STa.