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Identification of transport abnormalities in duodenal mucosa and duodenal enterocytes from patients with cystic fibrosis.

Authors
  • Pratha, V S
  • Hogan, D L
  • Martensson, B A
  • Bernard, J
  • Zhou, R
  • Isenberg, J I
Type
Published Article
Journal
Gastroenterology
Publisher
Elsevier
Publication Date
Jun 01, 2000
Volume
118
Issue
6
Pages
1051–1060
Identifiers
PMID: 10833480
Source
Medline
License
Unknown

Abstract

These findings implicate CFTR in NL duodenal alkaline transport and its absence in CF. Although duodenal bicarbonate secretion is impaired in CF tissues, alternate pathway(s) likely exist that can be activated by carbachol and STa.

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