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Identification of Recurrence Sites Following Post-Prostatectomy Treatment for Prostate Cancer Using 11C-Choline Positron Emission Tomography and Multiparametric Pelvic Magnetic Resonance Imaging.

Authors
  • Nehra, Avinash1
  • Parker, William P1
  • Haloi, Rimki1
  • Park, Sean S2
  • Mynderse, Lance A1
  • Lowe, Val J3
  • Davis, Brian J2
  • Quevedo, J Fernando4
  • Johnson, Geoffrey B3
  • Kwon, Eugene D1
  • Karnes, R Jeffrey5
  • 1 Department of Urology, Mayo Clinic, Rochester, Minnesota.
  • 2 Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota.
  • 3 Department of Radiology, Mayo Clinic, Rochester, Minnesota.
  • 4 Department of Medical Oncology, Mayo Clinic, Rochester, Minnesota.
  • 5 Department of Urology, Mayo Clinic, Rochester, Minnesota. Electronic address: [email protected]
Type
Published Article
Journal
The Journal of urology
Publication Date
Sep 12, 2017
Identifiers
DOI: 10.1016/j.juro.2017.09.033
PMID: 28916273
Source
Medline
Keywords
License
Unknown

Abstract

The combination of 11C-choline positron emission tomography/computerized tomography and multiparametric magnetic resonance imaging successfully identified patterns of recurrence after postoperative radiotherapy and/or androgen deprivation therapy at a median prostate specific antigen of less than 4 ng/ml. Half of this cohort had local only recurrence and/or a low disease burden limited to pelvic lymph nodes. These patients may benefit from additional local therapy. These data and this analysis may facilitate the evaluation of such patients with biochemically recurrent prostate cancer.

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