Affordable Access

The identification of a heparin-binding protein on the surface of bovine sperm.

Authors
  • Hurst, R E
  • Bynum, R L
  • Einfeldt, S E
  • Roy, J B
Type
Published Article
Journal
Biochemical and biophysical research communications
Publication Date
May 31, 1988
Volume
153
Issue
1
Pages
289–293
Identifiers
PMID: 2837205
Source
Medline
License
Unknown

Abstract

We report the identification of a sperm surface protein which binds tightly to heparin. The protein was isolated by affinity chromatography on heparin agarose, and its affinity for heparin was confirmed by electrophoresis in the presence of heparin under non-denaturing conditions. The protein consists of a single polypeptide chain with a molecular weight of 45,000, as determined by electrophoresis under denaturing conditions. The protein may bind glycosaminoglycans in vivo and play a part in initiating the capacitation/acrosome reaction.

Report this publication

Statistics

Seen <100 times