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Hypoxia-inducible factor-1 is central to cardioprotection: a new paradigm for ischemic preconditioning.

Authors
  • Eckle, Tobias
  • Köhler, David
  • Lehmann, Rainer
  • El Kasmi, Karim
  • Eltzschig, Holger K
Type
Published Article
Journal
Circulation
Publisher
Ovid Technologies Wolters Kluwer -American Heart Association
Publication Date
Jul 08, 2008
Volume
118
Issue
2
Pages
166–175
Identifiers
DOI: 10.1161/CIRCULATIONAHA.107.758516
PMID: 18591435
Source
Medline
License
Unknown

Abstract

Taken together, these studies provide evidence for a critical role of HIF-1 in ischemic preconditioning via enhancing purinergic signaling pathways.

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