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Hypoxia-induced deregulation of miR-126 and its regulative effect on VEGF and MMP-9 expression.

Authors
  • Ye, Panpan
  • Liu, Jian
  • He, Fengying
  • Xu, Wen
  • Yao, Ke
Type
Published Article
Journal
International journal of medical sciences
Publication Date
Jan 01, 2014
Volume
11
Issue
1
Pages
17–23
Identifiers
DOI: 10.7150/ijms.7329
PMID: 24396282
Source
Medline
Keywords
License
Unknown

Abstract

miR-126 is down-regulated under hypoxic condition both in vitro and in vivo and may halt the hypoxia-induce neovascularization by suspending the cell cycle progression and inhibiting the expression of VEGF and MMP-9.

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