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The hypoxanthine level in cord blood--a potential indicator of foetal hypoxia.

Authors
Type
Published Article
Journal
Physiologia Bohemoslovaca
Publication Date
Volume
34
Issue
2
Pages
173–176
Identifiers
PMID: 3161107
Source
Medline

Abstract

Hypoxia is one of the commonest causes of perinatal morbidity and mortality. The worst affected are tissues with high oxygen consumption, in particular nervous tissue (Trojan 1978). Criteria enabling prompt and reliable evaluation of the length and intensity of hypoxia are therefore being sought (Saugstad 1975a,b, Tuchschmidt et al .1981, O'Connor et al. 1981a,b). In recent years, conflicting information has appeared in the literature on the possibilities of utilizing the hypoxanthine and xanthine level in body fluids as an indicator of oxygen deficiency (Saugstad 1975a, Tuchschmidt et al. 1981). We therefore tested this criterion in newborn infants at risk from intrauterine hypoxia.

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