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Hypothermia and neurologic outcome in patients following cardiac arrest: should we be hot to cool off our patients?

Authors
  • Smith, Teresa L
  • Bleck, Thomas P
Type
Published Article
Journal
Critical care (London, England)
Publication Date
Oct 01, 2002
Volume
6
Issue
5
Pages
377–380
Identifiers
PMID: 12398769
Source
Medline
License
Unknown

Abstract

Hypothermia as a protectant of neurologic function in the treatment of cardiac arrest patients, although not a new concept, is now supported by two recent randomized, prospective clinical trials. The basic science research in support of the effects of hypothermia at the cellular and animal levels is extensive. The process of cooling for cerebral protection holds potential promise for human resuscitation efforts in multiple realms. It appears that, at least, those patients who suffer a witnessed cardiac arrest with ventricular fibrillation and early restoration of spontaneous circulation, such as those who were included in the European and Australian trials (discussed here), should be considered for hypothermic therapy.

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