Hypogonadism in patients with acromegaly: data from the multi-centre acromegaly registry pilot study.
- Published Article
- Publication Date
Feb 01, 2001
We developed a web-based acromegaly patient registry and used it to show that hypogonadism is a frequent consequence of acromegaly, even in patients with microadenomas, who are not at risk from hypopituitarism due to local mass effects. We also demonstrated that prolactin and GH hypersecretion contribute to the pathogenesis of hypogonadism in acromegaly, and that hypogonadism may occur in microadenoma patients even in the absence of hyperprolactinaemia.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/11207632