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Hypervalent iodine-catalyzed oxidative functionalizations including stereoselective reactions.

Authors
  • Singh, Fateh V
  • Wirth, Thomas
Type
Published Article
Journal
Chemistry - An Asian Journal
Publisher
Wiley (John Wiley & Sons)
Publication Date
Apr 01, 2014
Volume
9
Issue
4
Pages
950–971
Identifiers
DOI: 10.1002/asia.201301582
PMID: 24523252
Source
Medline
Keywords
License
Unknown

Abstract

Hypervalent iodine chemistry is now a well-established area of organic chemistry. Novel hypervalent iodine reagents have been introduced in many different transformations owing to their mild reaction conditions and environmentally friendly nature. Recently, these reagents have received particular attention because of their applications in catalysis. Numerous hypervalent iodine-catalyzed oxidative functionalizations such as oxidations of various alcohols and phenols, α-functionalizations of carbonyl compounds, cyclizations, and rearrangements have been developed successfully. In these catalytic reactions stoichiometric oxidants such as mCPBA or oxone play a crucial role to generate the iodine(III) or iodine(V) species in situ. In this Focus Review, recent developments of hypervalent iodine-catalyzed reactions are described including some asymmetric variants. Catalytic reactions using recyclable hypervalent iodine catalysts are also covered.

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