Hypersplenism is characterized by a significant reduction in one or more of the cellular elements of the blood in the presence of normocellular or hypercellular bone marrow and splenomegaly. The incidence of hypersplenism in patients with cirrhosis and portal hypertension is high. In rare cases the hyperslenism is symptomatic with bleeding disorders or hemolytic anemia. In this situation the splenectomy is the therapy of choice. The arterial partial embolisation is a good alternative procedure in patients with high risk of operation.