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Hyperpolarized 3He and 129Xe MR imaging in healthy volunteers and patients with chronic obstructive pulmonary disease.

Authors
  • Kirby, Miranda
  • Svenningsen, Sarah
  • Owrangi, Amir
  • Wheatley, Andrew
  • Farag, Adam
  • Ouriadov, Alexei
  • Santyr, Giles E
  • Etemad-Rezai, Roya
  • Coxson, Harvey O
  • McCormack, David G
  • Parraga, Grace
Type
Published Article
Journal
Radiology
Publisher
Radiological Society of North America
Publication Date
Nov 01, 2012
Volume
265
Issue
2
Pages
600–610
Identifiers
DOI: 10.1148/radiol.12120485
PMID: 22952383
Source
Medline
License
Unknown

Abstract

In patients with COPD, the VDP obtained with hyperpolarized 29Xe MR imaging was significantly greater than that with 3He MR imaging, suggesting incomplete or delayed filling of lung regions that may be related to the different properties of 129Xe gas and physiologic and/or anatomic abnormalities in COPD.

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