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Hyperpigmentation in megaloblastic anemia.

Authors
Type
Published Article
Journal
Journal of the American Academy of Dermatology
0190-9622
Publisher
Elsevier
Publication Date
Volume
12
Issue
5 Pt 2
Pages
914–917
Identifiers
PMID: 3998224
Source
Medline
License
Unknown

Abstract

Generalized hyperpigmentation developed over 2 years in a 65-year-old woman. A diagnosis of pernicious anemia was made, and treatment with vitamin B12 led to complete reversion of her hyperpigmentation to normal. Literature pertinent to hyperpigmentation and its association with megaloblastic anemias is reviewed and several possible mechanisms are mentioned.

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