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Hypercholesterolaemia and lipid lowering treatment do not affect the acute endogenous fibrinolytic capacity in vivo.

Authors
  • Newby, D E
  • Witherow, F N
  • Wright, R A
  • Bloomfield, P
  • Ludlam, C A
  • Boon, N A
  • Fox, K A A
  • Webb, D J
Type
Published Article
Journal
Heart
Publisher
BMJ
Publication Date
Jan 01, 2002
Volume
87
Issue
1
Pages
48–53
Identifiers
PMID: 11751664
Source
Medline
License
Unknown

Abstract

Hypercholesterolaemia and lipid lowering treatment cause no demonstrable effects on acute substance P induced t-PA release in vivo. This suggests that the preventative benefits of lipid lowering treatment are unlikely to be mediated by improvements in endogenous fibrinolysis.

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