Hypercalcemia complicating childhood malignancies: a report of seven cases with some pathophysiological considerations.
- Published Article
- Publication Date
Dec 01, 1979
A group of seven children with different malignant processes presenting with hypercalcemia was studied. Bone destruction, diffuse metabolic abnormalities, abnormal acid-base homeostasis and recurrent hypercalcemia characterized these patients. A different mechanism leading to the production of hypercalcemia and/or bone destruction by cancer cells is considered. The results of this report suggest that parathyroid hormone production (P.T.H.) by the parathyroid glands is normal and that ectopic secretion of PTH or PTH-like material is negligible in these cases.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/389412