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Human rhinovirus infection causes different DNA methylation changes in nasal epithelial cells from healthy and asthmatic subjects.

Authors
  • 1
  • 1 Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. [email protected]
Type
Published Article
Journal
BMC Medical Genomics
1755-8794
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Volume
7
Pages
37–37
Identifiers
DOI: 10.1186/1755-8794-7-37
PMID: 24947756
Source
Medline
License
Unknown

Abstract

We describe for the first time that Human rhinovirus infection causes DNA methylation changes in airway epithelial cells that differ between asthmatic and healthy subjects. These epigenetic differences may possibly explain the mechanism by which respiratory viruses cause asthma exacerbations.

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