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Human performance: a role for the ACE genotype?

Authors
  • Jones, Alun
  • Montgomery, Hugh E
  • Woods, David R
Type
Published Article
Journal
Exercise and sport sciences reviews
Publication Date
Oct 01, 2002
Volume
30
Issue
4
Pages
184–190
Identifiers
PMID: 12398116
Source
Medline
License
Unknown

Abstract

The I allele of the angiotensin I-converting enzyme (ACE) gene is associated with lower ACE activity and endurance performance; an excess occurs in elite distance runners, rowers, and mountaineers, perhaps secondary to enhanced muscle efficiency. Conversely, the D allele is associated with training-related strength gain and elite power-oriented performance secondary to increased ACE and angiotensin II, a growth factor.

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