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Human gene (c-fes) related to the onc sequences of Snyder-Theilen feline sarcoma virus.

Authors
  • G Franchini
  • E P Gelmann
  • R Dalla-Favera
  • R C Gallo
  • F Wong-Staal
Publication Date
Aug 01, 1982
Source
PMC
Keywords
License
Unknown

Abstract

The onc gene (v-fes) of the acutely transforming feline sarcoma virus (Snyder-Theilen strain) has homologous cellular sequences (c-fes) in all vertebrate species, including humans. We isolated from a human DNA library recombinant phages containing overlapping c-fes sequences. The human c-fes locus spans a region of 3.4 kilobases and contains 1.4 kilobases of DNA homologous to the viral onc sequence interspersed with three intervening sequences.

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