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Human epidermal growth factor receptor 2 status and interval breast cancer in a population-based cancer registry study.

Authors
  • Musolino, Antonino
  • Michiara, Maria
  • Conti, Giovanni Maria
  • Boggiani, Daniela
  • Zatelli, Marella
  • Palleschi, Dario
  • Bella, Maria Angela
  • Sgargi, Paolo
  • Di Blasio, Beatrice
  • Ardizzoni, Andrea
Type
Published Article
Journal
Journal of Clinical Oncology
Publisher
American Society of Clinical Oncology
Publication Date
Jul 01, 2012
Volume
30
Issue
19
Pages
2362–2368
Identifiers
DOI: 10.1200/JCO.2011.37.6434
PMID: 22585698
Source
Medline
License
Unknown

Abstract

This population-based cancer registry study demonstrated that HER2-positive tumors account for a substantial proportion of mammographic screening failure. The distribution of biologic characteristics in screen-detected cancers differs from that observed in interval cancers and may account in part for the more aggressive behavior of interval-detected cases.

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