Human breast carcinoma: heterotransplantation to newborn rats.

I Benjamin; H Pinkerton

Human breast carcinoma: heterotransplantation to newborn rats.

Authors

Benjamin, I
Pinkerton, H

Type

Published Article

Journal

Cancer Letters

Publisher

Elsevier

Publication Date

Mar 01, 1976

Volume

1

Issue

4

Pages

203–206

Identifiers

PMID: 1016945

Source

Medline

License

Unknown

Abstract

Cultured cells from a human breast carcinoma (HBC) were injected subcutaneously in newborn cortisone-treated Sprague-Dawley rats (CNBR). Tumors of predominantly epithelial nature appeared in all within 30 days, and wipespread metastases occured often. Cells cultured from these tumors rapidly produced similar tumors in CNBR. Rat-to-rat passage by implanting fragments of tumor tissue was 100% successful in CNBR. The in vivo model described is simple and inexpensive.

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. This record was last updated on 06/09/2018 and may not reflect the most current and accurate biomedical/scientific data available from NLM. The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/1016945

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