Affordable Access

Huachansu, containing cardiac glycosides, enhances radiosensitivity of human lung cancer cells.

Authors
  • Wang, Li
  • Raju, Uma
  • Milas, Luka
  • Molkentine, David
  • Zhang, Zhen
  • Yang, Peiying
  • Cohen, Lorenzo
  • Meng, Zhiqiang
  • Liao, Zhongxing
Type
Published Article
Journal
Anticancer Research
Publisher
International Institute of Anticancer Research
Publication Date
Jun 01, 2011
Volume
31
Issue
6
Pages
2141–2148
Identifiers
PMID: 21737634
Source
Medline
License
Unknown

Abstract

HCS-enhanced radiosensitivity of human lung cancer lines appeared to be p53-dependent. Inhibition of DNA repair and increase in radiation-induced apoptosis may have served as underlying mechanisms. These data suggest that HCS may have potential to improve the efficacy of radiotherapy.

Report this publication

Statistics

Seen <100 times