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Huachansu, containing cardiac glycosides, enhances radiosensitivity of human lung cancer cells.

Authors
Type
Published Article
Journal
Anticancer Research
1791-7530
Publisher
International Institute of Anticancer Research
Publication Date
Volume
31
Issue
6
Pages
2141–2148
Identifiers
PMID: 21737634
Source
Medline
License
Unknown

Abstract

HCS-enhanced radiosensitivity of human lung cancer lines appeared to be p53-dependent. Inhibition of DNA repair and increase in radiation-induced apoptosis may have served as underlying mechanisms. These data suggest that HCS may have potential to improve the efficacy of radiotherapy.

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