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HSV-1 antigens and DNA in the corneal explant buttons of patients with non-herpetic or clinically atypical herpetic stromal keratitis.

Authors
  • Garweg, Justus Gerhard
  • Russ, Christiane Elisabeth
  • Schellhorn, Marc
  • Böhnke, Matthias
  • Halberstadt, Markus
Type
Published Article
Journal
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie
Publication Date
Sep 01, 2003
Volume
241
Issue
9
Pages
734–739
Identifiers
PMID: 12827375
Source
Medline
License
Unknown

Abstract

Since the detection frequencies for HSV-1 antigens and DNA were comparable in the HSK and non-HSK groups, Herpes may play an underestimated and as yet undefined role in non-herpetic and clinically atypical herpetic stromal keratitis, either as a primary trigger of the disease or as a secondary contributor to it. In this category of individuals, early anti-herpetic therapy should be considered if patients do not respond in the expected manner to treatment for non-herpetic stromal keratitis.

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