Affordable Access

deepdyve-link deepdyve-link
Publisher Website

HOXB7 promotes invasion and predicts survival in pancreatic adenocarcinoma.

Authors
  • Nguyen Kovochich, Anne
  • Arensman, Michael
  • Lay, Anna R
  • Rao, Nagesh P
  • Donahue, Timothy
  • Li, Xinmin
  • French, Samuel W
  • Dawson, David W
Type
Published Article
Journal
Cancer
Publisher
Wiley (John Wiley & Sons)
Publication Date
Feb 01, 2013
Volume
119
Issue
3
Pages
529–539
Identifiers
DOI: 10.1002/cncr.27725
PMID: 22914903
Source
Medline
License
Unknown

Abstract

HOXB7 is frequently overexpressed in PDAC, specifically promotes invasive phenotype, and is associated with lymph node metastasis and worse survival outcome. HOXB7 and its downstream targets may represent novel clinical biomarkers or targets of therapy for inhibiting the invasive and metastatic capacity of PDAC.

Report this publication

Statistics

Seen <100 times