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HOXB7 promotes invasion and predicts survival in pancreatic adenocarcinoma.

Authors
Type
Published Article
Journal
Cancer
1097-0142
Publisher
Wiley Blackwell (John Wiley & Sons)
Publication Date
Volume
119
Issue
3
Pages
529–539
Identifiers
DOI: 10.1002/cncr.27725
PMID: 22914903
Source
Medline
License
Unknown

Abstract

HOXB7 is frequently overexpressed in PDAC, specifically promotes invasive phenotype, and is associated with lymph node metastasis and worse survival outcome. HOXB7 and its downstream targets may represent novel clinical biomarkers or targets of therapy for inhibiting the invasive and metastatic capacity of PDAC.

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