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How I treat anemia in older adults.

Authors
  • Oyedeji, Charity I1, 2
  • Artz, Andrew S3
  • Cohen, Harvey Jay2, 4
  • 1 Division of Hematology, Department of Medicine, Duke University School of Medicine, Durham, NC.
  • 2 Duke Claude D. Pepper Older Americans Independence Center, Durham, NC.
  • 3 City of Hope Medical Center, Duarte, CA.
  • 4 Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, NC.
Type
Published Article
Journal
Blood
Publisher
American Society of Hematology
Publication Date
Jan 18, 2024
Volume
143
Issue
3
Pages
205–213
Identifiers
DOI: 10.1182/blood.2022017626
PMID: 36827619
Source
Medline
Language
English
License
Unknown

Abstract

With the global growing older adult population, clinicians face the common, yet complex challenge of how to evaluate and manage anemia in this population. Older age predisposes to common causes of anemia such as nutritional deficiencies, inflammatory disorders, chronic kidney disease, and hematologic malignancies. Failure to diagnose and appropriately manage anemia may result in decreased quality of life, impaired cognition, impaired mobility, and increased mortality. Anemia diagnosis in older adults presents a diagnostic conundrum because anemia may have a single cause, may be multifactorial, or may have no apparent cause even after an extensive evaluation. We believe a systematic approach to diagnosis ensures appropriate testing and avoids the pitfall of undertreatment and overtreatment. In this article we present our recommended approach through common scenarios for the management of anemia in the older adult. © 2024 American Society of Hematology. Published by Elsevier Inc. Licensed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0), permitting only noncommercial, nonderivative use with attribution. All other rights reserved.

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