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Houttuyniacordata Thunb. polysaccharides ameliorates lipopolysaccharide-induced acute lung injury in mice.

Authors
  • Xu, Yan-Yan1
  • Zhang, Yun-Yi2
  • Ou, Ying-Ye1
  • Lu, Xiao-Xiao1
  • Pan, Ling-Yu1
  • Li, Hong1
  • Lu, Yan3
  • Chen, Dao-Feng4
  • 1 Department of Pharmacology, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai, China. , (China)
  • 2 Department of Pharmacology, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai, China. Electronic address: [email protected] , (China)
  • 3 Department of Pharmacognosy, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai, China. , (China)
  • 4 Department of Pharmacognosy, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai, China. Electronic address: [email protected] , (China)
Type
Published Article
Journal
Journal of ethnopharmacology
Publication Date
Sep 15, 2015
Volume
173
Pages
81–90
Identifiers
DOI: 10.1016/j.jep.2015.07.015
PMID: 26190353
Source
Medline
Keywords
License
Unknown

Abstract

These results indicate that HCP may alleviate LPS induced lung inflammatory injury, which may be associated with its inhibitory effect on the over activation of complement and macrophages. This suggests a potential role to treat ALI.

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