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The host response to herpes simplex virus infection.

Authors
  • Pollara, Gabriele
  • Katz, David R
  • Chain, Benjamin M
Type
Published Article
Journal
Current opinion in infectious diseases
Publication Date
Jun 01, 2004
Volume
17
Issue
3
Pages
199–203
Identifiers
PMID: 15166821
Source
Medline
License
Unknown

Abstract

A greater understanding of the importance of dendritic cells in driving viral immunity, and of the ligands that activate these cells and the cytokines they secrete, has provided novel vaccination strategies. The delivery of immunomodulatory genes together with viral antigens, for example by DNA vaccination, may harness the full potential of dendritic cells, and achieve the goal of effective immunological control of herpes simplex virus.

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