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[Hormone replacement therapy in postmenopausal women and cardiovascular risk].

Authors
  • Karam, C
  • Bourmayan, C
  • Desnos, M
  • Guérot, C
Type
Published Article
Journal
Annales de Cardiologie et d Angéiologie
Publisher
Elsevier
Publication Date
Apr 01, 1995
Volume
44
Issue
4
Pages
195–201
Identifiers
PMID: 7632028
Source
Medline
License
Unknown

Abstract

Although the cardiovascular effects of hormone replacement therapy of menopause have been controversial for a long time, the benefit of this treatment currently appears to be well established, despite the methodological problems of most studies and the absence of definitive demonstration by a prospective randomized study. The mechanism of this favourable action appears to be multifactorial with, in particular, an improvement of the lipid profile. In the absence of any gynaecological contraindication, the combination of a natural oestrogen and a progestogen devoid of any androgenic effect therefore appears to be the preferable treatment in postmenopausal women, especially as its cardiological value is added to other important and clearly documented actions.

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