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[Hormonal-metabolic disorders in children with diabetes mellitus in the preclinical stage of diabetic retinopathy].

Authors
  • Kniazev, Iu A
  • Dudnikova, L K
  • Vakhrusheva, L L
  • Shiriaeva, L I
  • Pozdniakov, A M
Type
Published Article
Journal
Pediatriia
Publication Date
Jan 01, 1992
Issue
2
Pages
32–35
Identifiers
PMID: 1513630
Source
Medline
License
Unknown

Abstract

A relationship was established between alterations in vessels of the fundus of the eye and diabetes mellitus standing, the character of metabolic disorders, hereditary load with regard to cardiovascular diseases. The risk factors of the development of the preclinical stage of diabetic retinopathy are as follows: hereditary load with regard to cardiovascular diseases, parship, an increase of the content of lactate, a reduction of the content of 2,3-diphosphoglycerophosphate, a rise of the content of glycosylated hemoglobin, high content of cholesterol esters in red blood cell membranes, of free cholesterol and malonic dialdehyde in blood serum, a decline of the level of phospholipids and a rise of cardiolipin content in red blood cell membranes, and increase of blood serum cortisol.

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