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[Hormonal disorders in patients with chronic pyelonephritis with nephrosclerosis and kidney failure].

Authors
  • Pavlov, S B
Type
Published Article
Journal
Likars'ka sprava / Ministerstvo okhorony zdorov'ia Ukraïny
Publication Date
Jan 01, 1998
Issue
1
Pages
139–142
Identifiers
PMID: 9621641
Source
Medline
License
Unknown

Abstract

Blood plasma content was studied of hydrocortisone, parathyroid hormone (PTH) and calcitonin in patients with chronic pyelonephritis (ChP) using methods of radioimmunologic and immunoenzymatic analyses. ChP patients had marked alterations of blood plasma levels of hydrocortisone, PTH and calcytonin, with the reduced levels of hydrocortisone and hypercalcitoninamia being noted during the early stages of nephrosclerosis. It is suggested that hydrocortisone and calcitonin content in blood of ChP patients might be used as indicators of state of the endocrine mechanisms controlling the renal connective tissue metabolism during the early stages of nephrosclerosis. The above measure will also be helpful in the assessment of activity of the sclerotic process in the kidneys, prognosis of the outcome of the medical condition, and development of treatment options of adequate pathogenetic therapy.

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