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Horizontal and Vertical Transmission of West Nile Virus by Aedes vexans (Diptera: Culicidae).

Authors
  • Anderson, John F1
  • Main, Andrew J2
  • Ferrandino, Francis J3
  • 1 Department of Entomology, Center for Vector Biology and Zoonotic Diseases, The Connecticut Agricultural Experiment Station, New Haven, CT.
  • 2 Department of Biology, American University in Cairo, Cairo, Egypt. , (Egypt)
  • 3 Department of Plant Pathology and Ecology, The Connecticut Agricultural Experiment Station, New Haven, CT.
Type
Published Article
Journal
Journal of Medical Entomology
Publisher
Oxford University Press
Publication Date
Sep 07, 2020
Volume
57
Issue
5
Pages
1614–1618
Identifiers
DOI: 10.1093/jme/tjaa049
PMID: 32188992
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

West Nile virus (family Flaviviridae, genus Flavivirus) first caused human and veterinary disease, and was isolated from Culex pipiens pipiens L. and Aedes vexans (Meigen) (Diptera: Culicidae) in the United States in 1999. We report that a Connecticut strain of Ae. vexans was competent to transmit West Nile virus both horizontally to suckling mice and vertically to its progeny in the laboratory. Horizontal transmission was first observed on day 6 post-exposure (pe). Daily horizontal transmission rates generally increased with the day post-virus exposure with highest rates of 67-100% recorded on days 28-30 pe. One female vertically transmitted West Nile virus on day 21 pe, but only after it had taken its third bloodmeal. Horizontal and vertical transmission may contribute to West Nile virus infection rates in Ae. vexans in summer, and vertical transmission provides a means of survival of West Nile virus during winter. © The Author(s) 2020. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For permissions, please e-mail: [email protected]

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