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HLA-DRB1 alleles associated with susceptibility or resistance to rheumatoid arthritis, articular deformities, and disability in Mexican Americans.

Authors
  • del Rincón, I
  • Escalante, A
Type
Published Article
Journal
Arthritis and rheumatism
Publication Date
Jul 01, 1999
Volume
42
Issue
7
Pages
1329–1338
Identifiers
PMID: 10403259
Source
Medline
License
Unknown

Abstract

HLA-DRB1 alleles containing the SE are associated with susceptibility to RA in Mexican Americans, and may also be associated with a more rapid development of articular deformities and disability. HLA-DRB1*08 appears to have a protective influence on RA susceptibility and disease severity in Mexican Americans.

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