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HLA-DQ beta typing and non-Asp57 alleles in IDDM and nondiabetic subjects in New Zealand.

Authors
  • Forbes, L V
  • Brown, L J
  • Scott, R S
Type
Published Article
Journal
Diabetes Care
Publisher
American Diabetes Association
Publication Date
Aug 01, 1993
Volume
16
Issue
8
Pages
1179–1183
Identifiers
PMID: 8104110
Source
Medline
License
Unknown

Abstract

HLA-DQ beta alleles are genetic susceptibility markers in New Zealand, and other Caucasian populations. Peak IDDM incidence levels observed in 1990-1992 in our population are in accordance with a high background population prevalence of non-Asp57 alleles. These results suggest that the high Canterbury incidence rates may be due to a large HLA-DQ beta non-Asp57 at-risk population.

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