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HIV viral load as an independent risk factor for tuberculosis in South Africa: collaborative analysis of cohort studies.

Authors
  • Fenner, Lukas1, 2, 3
  • Atkinson, Andrew4
  • Boulle, Andrew5
  • Fox, Matthew P6, 7
  • Prozesky, Hans8
  • Zürcher, Kathrin1
  • Ballif, Marie1
  • Furrer, Hansjakob4
  • Zwahlen, Marcel1
  • Davies, Mary-Ann9
  • Egger, Matthias1, 9
  • 1 Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland. , (Switzerland)
  • 2 Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland. , (Switzerland)
  • 3 University of Basel, Basel, Switzerland. , (Switzerland)
  • 4 Department of Infectious Diseases, Bern University Hospital, University of Bern, Bern, Switzerland. , (Switzerland)
  • 5 Khayelitsha ART Programme, Médecins Sans Frontières, Cape Town, South Africa. , (South Africa)
  • 6 Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. , (South Africa)
  • 7 Departments of Epidemiology and Global Health, Boston University, Boston, MA, USA.
  • 8 Division of Infectious Diseases, Department of Medicine, University of Stellenbosch and Tygerberg Hospital, Cape Town, South Africa. , (South Africa)
  • 9 Centre for Infectious Disease Epidemiology and Research (CIDER), School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa. , (South Africa)
Type
Published Article
Journal
Journal of the International AIDS Society
Publisher
Wiley (John Wiley & Sons)
Publication Date
Jun 23, 2017
Volume
20
Issue
1
Pages
21327–21327
Identifiers
DOI: 10.7448/IAS.20.1.21327
PMID: 28691438
Source
Medline
Keywords
License
Unknown

Abstract

Our results indicate that ongoing HIV replication is an important risk factor for TB, regardless of CD4 cell counts, and underline the importance of early ART start and retention on ART.

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