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HIV pathogenesis: the first cut is the deepest

Authors
  • Picker, Louis J1
  • Watkins, David I2
  • 1 Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, 97006, USA , Beaverton (United States)
  • 2 University of Wisconsin, Madison, Wisconsin, 53706, USA , Madison (United States)
Type
Published Article
Journal
Nature Immunology
Publisher
Springer Nature
Publication Date
May 01, 2005
Volume
6
Issue
5
Pages
430–432
Identifiers
DOI: 10.1038/ni0505-430
Source
Springer Nature
License
Yellow

Abstract

HIV pathogenesis is thought of as a chronic infection involving slow degradation of immunity that ultimately leads to AIDS. This scenario, however, could reflect the decay of an immune system mortally wounded during acute HIV infection.

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