Affordable Access

Histopathological classification of esophageal carcinomas.

Authors
  • Vellone, Valerio Gaetano
  • Zannoni, Gian Franco
  • Mulè, Antonino
  • Lauriola, Libero
Type
Published Article
Journal
Rays
Publication Date
Jan 01, 2006
Volume
31
Issue
1
Pages
57–61
Identifiers
PMID: 16999377
Source
Medline
License
Unknown

Abstract

Esophageal carcinomas are steadily rising worldwide; they rank sixth among tumors. Adenocarcinoma is the most common histological type in Western countries while squamous carcinoma is more common in the developing countries. Both types are preceded by pre-neoplastic lesions rappresented by Barrett's esophagus for adenocarcinoma and low and high grade dysplasia for squamous carcinoma. Some continuity exists between dysplastic lesions and frankly invasive tumors. Moreover rare hystological types have been described. The surgical pathologist plays an important role in evaluating small endoscopic biopsies as well as in examining surgical specimens from esophagectomy. In the former case the role is exclusively diagnostic while in the latter surgical radicality, cancer stage and outcomes of neoadjuvant therapies are assessed. All these data are crucial not only for prognosis but also for therapy planning.

Report this publication

Statistics

Seen <100 times