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Histopathologic characterization of lung adenocarcinoma in relation to fluorine-18-fluorodeoxyglucose uptake on positron emission tomography.

Authors
  • Domen, Hiromitsu
  • Hida, Yasuhiro
  • Okamoto, Shozo
  • Hatanaka, Kanako C
  • Hatanaka, Yutaka
  • Kaga, Kichizo
  • Tamaki, Nagara
  • Hirano, Satoshi
  • Matsuno, Yoshihiro
Type
Published Article
Journal
Japanese Journal of Clinical Oncology
Publisher
Oxford University Press
Publication Date
Sep 01, 2013
Volume
43
Issue
9
Pages
874–882
Identifiers
DOI: 10.1093/jjco/hyt100
PMID: 23911772
Source
Medline
Keywords
License
Unknown

Abstract

More histopathologic factors are known to correlate with poor prognosis in lung adenocarcinomas showing high maximum standardized uptake values than in those showing low maximum standardized uptake values. Therefore, prognostication of patients with a resectable lung adenocarcinoma on the basis of preoperative fluorine-18-fluorodeoxyglucose uptake is histopathologically valid. Such observations may also help us to clarify the pathobiological mechanism responsible for the increased fluorine-18-fluorodeoxyglucose uptake in lung adenocarcinomas with a poor prognosis.

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